Assess commercial potential

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When you're thinking about a start-up, there are some important questions you need to answer early on.

If you’re thinking about founding a start-up, there are many tools to help you think about:

  • what product or service you offer
  • what would make customers pay for this offering.

When you’ve made these decisions, you can develop your ‘value proposition’.

This is a statement describing how your product or service solves a problem for your customers. For example, it could remove obstacles that prevent them from doing their jobs or enhance their ability to perform their jobs.

Tools to help you

Tools to help you

A tool used by many successful start-up founders is the Value Proposition Canvas from Strategyzer. There is also a video explaining how to complete the canvas. This tool and others like it help you see your proposed product or service from the viewpoint of your potential customers.

The Value Proposition Canvas helps you answer questions like:

  • What is your customer’s job? What are they aiming to do?
  • What obstacles, or ‘pains’, stop them today from doing their job? What causes them to fail?
  • What ‘gains’ define success for them in their job?
  • What product or service could you offer to this customer?
  • What features of your product or service address each of your customer’s pains and gains?

A successful product or service relieves the target customer's pain and creates gain. There is a close fit between:

  • the left side of the Value Proposition Canvas, describing the customer’s job, pains, and gains
  • and the right side, describing your product or service.

Completing an exercise like this often leads to a change in thinking about exactly who your target customers are and what you’re offering them:

  • Who cares most about the problem your product or service is solving?
  • Who feels the most pain from this problem today, and who will experience the most gain when it is solved?
  • What features of your product or service relieve this pain, and create this gain?
  • Are you spending time developing other features that don’t do this?

    Life sciences start-ups

    Life sciences start-ups often operate in a five-sided market, which includes the following players:

    • Patient – the end user of the start-up’s product or service.
    • Physician – the medical professional who prescribes or directs the patient to use the product or service.
    • Provider – the pharmaceutical or medical device supplier who provides the product or service.
    • Payer – the organisation, for example a private or government-run insurer, who pays for the product or service.
    • Regulator – the government body that decides if life sciences products and services can be used in a particular country. This is different from the insurer.

    If you are considering a life sciences start-up, you are a provider in this scenario. You should complete the Value Proposition Canvas exercise for all five players. This will help you understand the value that your proposed product or service brings to each of them. The role of the regulator is especially important in life sciences.

    How would the start-up make money?

    How would the start-up make money?

    When you’ve identified potential customers for your product or service, other tools can help you consider how to build a commercially sustainable business.

    Completing a Business Model Canvas will help you consider questions like:

    • Of all the people who will interact with my product or service, which ones are my customers, the ones who will pay me for it? This exercise might also help you identify end users of your product or service – your customers’ customers.
    • What am I offering these customers that they don’t already get from their existing suppliers?
    • Is my offering valuable enough for customers to consider switching from their existing supplier to a new, unknown supplier (my start-up)?
    • How will I communicate with my customers and deliver my product or service to them? Will I use direct sales, distributors or the internet? What will this cost me?
    • Of all the things that must be done to create and deliver my product or service to my target customers, what subset of these are critical to my business? What resources will I need to do these? What will these resources cost me? What partnerships might give me the other things I need? And what will these partnerships cost me?
    • What will my costs be over the next 12 months? The next five years?
    • Will my revenues be more than my costs?

    Completing a first pass at the Value Proposition Canvas and Business Model Canvas will probably take less than an hour. Remember that both processes are iterative and will probably lead to you revising your plans. For example, you may re-think your target customers and your proposed product or service.

      Life sciences start-ups

      The most significant difference between life sciences start-ups and other types of start-up is the need to comply with regulations to sell life sciences products and services. These can mean higher costs and a longer time needed.

      These regulations are driven by safety. They are defined and enforced by bodies such as the US Food and Drug Administration and the Australian Department of Health’s Therapeutic Goods Administration. The cost of a life sciences start-up depends on the industry:

      • To bring a single pharmaceutical drug for human use to market currently takes, on average, a decade and more than $US1 billion in research and development investment.
      • The development cost for other types of life sciences products and services for humans is typically lower. For example, diagnostics, medical devices and digital health.
      • For veterinary products and services costs are lower again, but the costs are still very high.
      • Products and services in many other industries are subject to regulations or standards. For example, food, cosmetics, consumer electronics and telecommunications. Here, the cost and time of compliance is significantly lower than in the life sciences.

      Often the only companies with the resources needed to bring a life sciences product to market are giant global pharmaceutical or medical device providers.

      The only way that many life sciences start-ups achieve impact is by being bought by one of these giants. Most life sciences start-ups don’t aim to supply their product directly to customers themselves, or to become profitable.

      Instead, they aim to create value by reducing the risks that come with their technology, for example through clinical studies. They then aim to be bought by a giant who will fund more development of the product and eventually bring it to market.

      If your proposed start-up is in this category, it’s worth reconsidering the Value Proposition Canvas exercise with:

      • a giant as the customer
      • your start-up itself as the product, to be bought by the giant.

      Think about:

      • What’s the value for the giant of buying your start-up versus developing a similar technology in-house?
      • What’s the value for the giant of buying your start-up versus any other start-ups that might be developing a similar product?

      You might find it helpful to imagine that the giant has completed the entire product development process, so that the product or service based on your technology is finally available for use.

      What value would it provide to patients, physicians and insurers? If these Value Proposition Canvases do not show a clear fit, then your start-up will not be an attractive acquisition target.

      When you’ve been through these exercises, complete a Business Model Canvas for your start-up as an acquisition target for a life sciences giant:

      • At what stage of the product development (and risk reduction) process will you aim to be acquired?
      • How much will it cost your start-up to reach this stage?
      • What sources of funding will you use?
      • How will you contact your target buyers, stay engaged with them, and make sure that they value your development?
      • What parts of your development will you do in-house and what parts will be outsourced?

      What will tell me if my ideas could succeed?

      What will tell me if my ideas could succeed?

      The Value Proposition Canvas from Strategyzer and the Business Model Canvas from Strategyzer help clarify your ideas about what your start-up’s business might be. They don’t, however, generate any objective evidence that these ideas will succeed.

      While a start-up inherently involves risk, you want strong evidence that these ideas will succeed before you commit your time, energy, reputation and potentially your family’s savings to it. The University will also want confidence in your business ideas before we support you.

      The most valuable way to find this evidence is the customer interview. Approaches like those used in the scientific method, familiar to many researchers, can be used here.

      Your goal is to identify the most important hypotheses (used here to mean untested business ideas) inherent in the canvases and validate them with data that’s as objective as possible, coming from discussions or interviews with potential customers.

      In this context, the word ‘customer’ includes end users, suppliers and industry experts as well as paying customers.

      In the early stages of developing your value proposition and business model, your goals in customer interviews are simply to learn:

      • what the jobs of the players in the industry are
      • what products and services they offer and to whom
      • how the industry works.

      As you revise your value proposition and business model based on what you learn from interviews, your goals in later customer interviews will be to validate your key hypotheses:

      • Focus first on exploring the most critical hypotheses. Focus on the ones which, if invalid, significantly change the whole canvas and the ones you know least about.
      • You’ll know that a hypothesis is validated if a few interviewees, in response to open-ended questions, offer the same information without your prompting.

      Customer interviews are a different type of conversation from those you may have had before:

      • It takes practice to conduct interviews that produce valuable information.
      • Customising the interview questions for your purposes takes thought and practice.

      For this reason, many pre-incubator programs for early-stage start-ups focus on customer interviews. This includes the University of Melbourne’s Translating Research at Melbourne (TRaM).

      Another similar program, CSIRO’s ON Prime, has participants conduct at least 100 customer interviews to validate their Value Proposition Canvas.

      This is a lot of work. It involves 100 interviews averaging 90 minutes each, including time to prepare, interview and synthesise. This is four weeks of full-time work. But the insight you’ll get from conducting these interviews is priceless, so this is work you and your co-founders must do yourselves – don’t delegate or outsource it.

      The customer interview philosophy described here is consistent with the Lean start-up methodology, pioneered in Silicon Valley, which aims to reduce the risk of new ventures failing through an iterative development process involving prospective customers.

      Customer interviews will not only give you a deep understanding of the problems that need to be solved, but also allow you to focus your resources on solving them.

      Get the best out of interviews

      Get the best out of interviews

      When conducting customer interviews, it’s important to:

      • Spend more time listening than talking.
      • Ask open-ended questions (don’t ‘lead the witness’). For example, you’ll learn more from saying, ‘I’d like to learn more about your job. What are you responsible for?’ than from ‘So, your job is to keep your company’s infrastructure running – is that right?’
      • Ask about actions, not intentions. The most valuable information will come from customers’ current or recent behaviour, not from statements about what they might do in future.
      • For example, if you’re investigating an idea for a new exercise regime, the question ‘How many times did you go to the gym last week?’ will give you more useful information than ‘How often do you go to the gym?’ (which is likely to uncover intentions rather than actual behaviour) or ‘Would you go to the gym to do X?’ (which invites speculation about possible future behaviour).
      • Avoid undue influence. Most people naturally want to help, and more often than not, an articulate researcher communicating their passion about their new idea and asking the interviewee whether it could be valuable to their company will get a supportive response, which might or might not translate into sales.
      • When asking for an interview, it’s best to be very general about what you’d like to discuss. For example, instead of saying ‘We’ve invented a new chemical that has higher efficiency and more stability than [compounds X and Y], and we think it will be very valuable in luminescent solar concentrators. Do you have time to help us validate this?’, it would be better to ask ‘We’re conducting research on compounds that might have applications in solar photovoltaics, and we want to learn about this market. Do you have time to help us by answering some questions?’
      • Avoid personal bias. When you have invested significant time and effort in developing an idea, it’s natural to seek validation of the idea’s value and to shy away from evidence to the contrary. But while it could be painful for you to find out that your idea has limited commercial value, the sooner you discover this, the better. The history of technology start-ups is littered with stories of founders who invested huge amounts of time and money developing products that had no value to their target customers. Customer interviews, carried out without bias, will help avoid this.
      • Remember that you’re gathering information, not selling anything. That will come later.

        Finding prospective customers

        How do prospective start-up founders meet potential customers to interview?

        • Your Faculty’s Business Development team member probably has relevant industry contacts and may be willing to introduce them or suggest places to meet them, for example at conferences and trade shows.
        • Always ask interviewees to suggest, and ideally introduce, other people you could talk to.
        • Don’t underestimate the power of the University’s brand. Most people are keen to help University researchers understand more about how their work might help the broader community, even if you’re ‘cold calling’ them.
        • Many start-up incubators and accelerators make customer interviews their primary focus, and help busy researchers carve out the time to conduct enough interviews to validate a value proposition.

          Life sciences start-ups

          If you’re considering a life sciences start-up, the goal of your customer interviews could be to establish:

          • Who are the patients, physicians, providers, payers and regulators relevant to your proposed product or service? If your start-up will operate in a five-sided market, those who use your product will not be those who pay for it. But to be successful, your start-up’s product must offer value to all of them.
          • Were your hypotheses about the jobs, pains, gains, and the value of your proposed product or service (or your start-up itself) to each of these groups correct?
          • Direct access to current patients can be difficult, as their physicians and hospitals are bound by confidentiality. What will you do to get validation of the Value Proposition Canvas for the final product for patients?
          • Were your hypotheses about your start-up’s Business Model Canvas correct?

          What impact am I really trying to achieve?

          What impact am I really trying to achieve?

          Many successful technology companies have one thing in common: their leaders articulate a clear, simple and ambitious vision of the company’s impact and the way it will change the world.

          One example is the vision of Dr Elaine Saunders. She is the co-founder of Melbourne-based hearing health disruptor Blamey Saunders hears. Her vision is:

          ‘Empowering you to take control of your hearing – making hearing health affordable and accessible.’

          The value proposition and business model canvases show some of the strategy your start-up will use to achieve your vision.

          As the start-up develops, this strategy may change as you learn more about your target customers. But your vision, once it’s established, is less likely to change.

          Simon Sinek is a leadership expert. As he explained in a TEDx talk, when a company leader articulates a clear and consistent vision, this fosters commitment from stakeholders. Stakeholders can be a start-up’s customers, end users, partners, team and investors. This commitment is needed to achieve major impact.

          We encourage you to invest time in developing a statement of your vision for your start-up. The challenge for most researchers is being ambitious enough. You need to step back from the details of the research to see how much it could change the world.

          One way to do this is to ask yourself a series of ‘what if ...?’ questions. Complete the Massive Canvas exercise in the StartUp Science® Toolkit.

            Life sciences start-ups

            Thinking big

            Dr Elaine Saunders’ version of the Massive Canvas for Blamey Saunders hears might have been:

            • What if we could develop hearing aids with lower cost and higher performance than our competitors?
            • What if we could develop an online, self-administered hearing test to enable people to diagnose and monitor their own hearing loss?
            • What if we could develop a smartphone-based system that enabled each of our customers to customise the set-up of our hearing aids for them, and dynamically optimise its performance for each environment?
            • What if we developed a sales and service website that older people are comfortable using? These are most of our customers.
            • What if we could deliver hearing aids with an order-of-magnitude improvement in accessibility, performance, ease of use, and affordability?
            • What if we eliminated poor hearing as a social barrier for older Australians?

            If you are considering a life sciences start-up, you are a provider in this scenario. You should complete the Value Proposition Canvas exercise for all five players. This will help you understand the value that your proposed product or service brings to each of them. The role of the regulator is especially important in life sciences.

            If not a start-up, then what?

            If not a start-up, then what?

            Even if you’re motivated to achieve impact with your research, you may realise after completing the value proposition and business model exercises that founding a start-up isn’t the right decision for you and your research. What now? Here are some options:

            • Partnering with an existing company. Perhaps you’ve concluded that although your research solves a real problem, the market has no room for a new start-up. In this case, your research could be valuable to established companies to improve their existing products.
            • Consider forming a partnership with one or more of these companies, in the form of joint research projects. Any resulting IP is usually transferred to the partner company through a license agreement.
            • Transferring the IP to a spin-out company, an entity that is at least partially owned and controlled by the University.
            • Redirecting your research. If your customer interviews identified a real problem that your current research does not solve, but that related research could, you can consider redirecting your research to solve the problem. If so, stay connected to the customers whose problem you aim to solve, as their feedback may be useful later.

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